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Research project
Research Team
Research project

ESTABLISHMENT OF DLBCL MODEL OF MOUSE

 [under construction!]


Establishment of DLBCL model of mouse: NGS mice were infused with DLBCL Sud-HL8 cells via subcutaneous injection to induce tumor. Luciferase gene expression can be observed one week post injection, and tumor model is stably established two weeks post injection. Said tumor cells express many DLBCL surface specific antigens, such as CD-19; thus establishment of said mouse model can accumulate the datum of in-vivo killing assay and safety issue, and be a pre-clinical platform for safety and efficacy of CAR-T cell therapy and also the foundation of clinical applications.  


ADD: 深圳市南山区粤兴二道6号虚拟大学园重点实验室平台二层   TEL: 075586725195   Email: gimi_trials@szgimi.org

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